Book chapter · Journal article
Towards the Development of Digital Twins for the Bio-manufacturing Industry
PROSYS - Process and Systems Engineering Centre, Department of Chemical and Biochemical Engineering, Technical University of Denmark1
Department of Chemical and Biochemical Engineering, Technical University of Denmark2
KT Consortium, Department of Chemical and Biochemical Engineering, Technical University of Denmark3
PILOT PLANT, Department of Chemical and Biochemical Engineering, Technical University of Denmark4
The bio-manufacturing industry, along with other process industries, now has the opportunity to be engaged in the latest industrial revolution, also known as Industry 4.0. To successfully accomplish this, a physical-to-digital-to-physical information loop should be carefully developed. One way to achieve this is, for example, through the implementation of digital twins (DTs), which are virtual copies of the processes.
Therefore, in this paper, the focus is on understanding the needs and challenges faced by the bio-manufacturing industry when dealing with this digitalized paradigm. To do so, two major building blocks of a DT, data and models, are highlighted and discussed. Hence, firstly, data and their characteristics and collection strategies are examined as well as new methods and tools for data processing.
Secondly, modelling approaches and their potential of being used in DTs are reviewed. Finally, we share our vision with regard to the use of DTs in the bio-manufacturing industry aiming at bringing the DT a step closer to its full potential and realization.
Language: | English |
---|---|
Publisher: | Springer |
Year: | 2021 |
Pages: | 1-35 |
Series: | Advances in Biochemical Engineering/biotechnology |
Journal subtitle: | Tools and Concepts for Smart Biomanufacturing |
ISBN: | 3030716597 , 3030716600 , 9783030716592 and 9783030716608 |
ISSN: | 16168542 and 07246145 |
Types: | Book chapter and Journal article |
DOI: | 10.1007/10_2020_142 |
ORCIDs: | L. Gargalo, Carina , Caño de Las Heras, Simoneta , Jones, Mark Nicholas , Udugama, Isuru , Mansouri, Seyed Soheil , Krühne, Ulrich and Gernaey, Krist V. |