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Book chapter

Emerging strategies in 3D printed tissue models for in vitro biomedical research

In Bioprinting — 2022, pp. 207-246
From

Biomimetics, Department of Health Technology, Technical University of Denmark1

Tailored Materials and Tissues, Biomimetics, Department of Health Technology, Technical University of Denmark2

Department of Health Technology, Technical University of Denmark3

Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark4

Colloids & Biological Interfaces, Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark5

Lund University6

University of Pavia7

3D bioprinting has the potential to provide a unified framework for the manufacturing of tissue models for biomedical research, including drug discovery, disease modeling, and regenerative medicine. However, it remains challenging to 3D print replicas of human tissues that have accurate cell types, cellular densities, extracellular matrix compositions, and that can be assayed in a minimally invasive manner for chronic studies.

Here, we review how recent breakthroughs in stem cell biology, tissue engineering, and materials science have led to novel 3D printing strategies that have the potential to solve these challenges.

Language: English
Publisher: Elsevier
Year: 2022
Pages: 207-246
Journal subtitle: From Multidisciplinary Design To Emerging Opportunities
ISBN: 0323854303 , 0323854311 , 9780323854306 and 9780323854313
Types: Book chapter
DOI: 10.1016/B978-0-323-85430-6.00007-8
ORCIDs: Cakal, Selgin D. and Lind, Johan U.

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