Conference paper
Integrated B1+ Mapping for Hyperpolarized 13C MRI in a Clinical Setup using Multi-Channel Receive Arrays
Department of Electrical Engineering, Technical University of Denmark1
Center for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark2
Center for Hyperpolarization in Magnetic Resonance, Centers, Technical University of Denmark3
University of California at San Francisco4
For hyperpolarized 13C MRI acquisitions aimed at metabolic rate constant estimation, the Bloch-Siegert shift enables encoding of the transmit field (B1+-field) amplitude within a single hyperpolarized substrate injection. This ability is needed since most clinical hyperpolarized MRI studies use inhomogeneous transmit coils, and because kinetic modeling based on incorrect flip angles can lead to incorrect rate constant estimations.
This study demonstrates the feasibility of integrated B1+ mapping for large volume thermal and hyperpolarized phantoms in a clinical setup using a clamshell transmit coil and a 16-channel receive array, and a 3D stack-of-spirals sequence. Phase-sensitive coil-combination was achieved using ESPIRiT.
| Language: | English |
|---|---|
| Year: | 2018 |
| Proceedings: | Joint Annual Meeting ISMRM-ESMRMB 2018 |
| Types: | Conference paper |
| ORCIDs: | Hansen, Rie Beck , Hanson, Lars G. and Ardenkjær-Larsen, Jan Henrik |
