Conference paper · Journal article
Microtubule's conformational cap
In
Book of Abstracts
—
1999, Volume 24, Issue 5, pp. 299-303
Abstract
The molecular mechanisms that allow elongation of the unstable microtubule lattice remain unclear. It is usually thought that the GDP-liganded tubulin lattice is capped by a small layer of GTP- or GDP-P(i)-liganded molecules, the so called "GTP-cap". Here, we point-out that the elastic properties of the microtubule lattice cause a difference in stability between the elongating tubulin sheet and the completed microtubule wall.
The implications of our observations for microtubule structure and dynamics are discussed.
| Language: | English |
|---|---|
| Publisher: | Niels Bohr Institute |
| Year: | 1999 |
| Pages: | 299-303 |
| Proceedings: | Topical Meeting on Biophysics-Biological Physics 1999 |
| ISSN: | 13473700 and 03867196 |
| Types: | Conference paper and Journal article |
| DOI: | 10.1247/csf.24.299 |
| ORCIDs: | Flyvbjerg, H. |
