Journal article
Cell-laden alginate hydrogels for the treatment of diabetes
University of the Basque Country1
Department of Health Technology, Technical University of Denmark2
Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark3
Biologically Inspired Material Engineering, Biotherapeutic Engineering and Drug Targeting, Department of Health Technology, Technical University of Denmark4
University of California at Los Angeles5
University of Verona6
University of Texas at Austin7
University of Groningen8
Gloriana Therapeutics, Inc.9
Introduction: Diabetes mellitus is an ever-increasing medical condition that currently suffers 1 of 11 adults who may have lifelong commitment with insulin injections. Cell-laden hydrogels releasing insulin may provide the ultimate means of correcting diabetes. Here, we provide insights of this cell-based approach including latest preclinical and clinical progress both from academia and industry.
Area covered: The present article focuses on reviewing latest advances in cell-laden hydrogels both from the technological and biological perspective. The most relevant clinical results including clinical trials are also discussed. Expert opinion: Current progress in technological issues (stem cells, devices, biomaterials) have contributed cell encapsulation science to have a very relevant progress in the field of diabetes treatment.
| Language: | English |
|---|---|
| Publisher: | Taylor & Francis |
| Year: | 2020 |
| Pages: | 1113-1118 |
| ISSN: | 17447593 and 17425247 |
| Types: | Journal article |
| DOI: | 10.1080/17425247.2020.1778667 |
| ORCIDs: | 0000-0002-0773-300X and Dolatshahi-Pirouz, Alireza |
