Journal article
Benchmark problems for transcranial ultrasound simulation: Intercomparison of compressional wave models
Université PSL1
University of North Carolina at Chapel Hill2
Foundation for Research on Information Technologies in Society3
University of Calgary4
University of Eastern Finland5
Neurophysics, Magnetic Resonance, Department of Health Technology, Technical University of Denmark6
Magnetic Resonance, Department of Health Technology, Technical University of Denmark7
Department of Health Technology, Technical University of Denmark8
Pontificia Universidad Católica de Chile9
Imperial College London10
Swiss Federal Institute of Technology Zurich11
Stanford University12
University of Utah13
City, University of London14
University College London15
Brno University of Technology16
Pennsylvania State University17
...and 7 moreComputational models of acoustic wave propagation are frequently used in transcranial ultrasound therapy, for example, to calculate the intracranial pressure field or to calculate phase delays to correct for skull distortions. To allow intercomparison between the different modeling tools and techniques used by the community, an international working group was convened to formulate a set of numerical benchmarks.
Here, these benchmarks are presented, along with intercomparison results. Nine different benchmarks of increasing geometric complexity are defined. These include a single-layer planar bone immersed in water, a multi-layer bone, and a whole skull. Two transducer configurations are considered (a focused bowl and a plane piston operating at 500 kHz), giving a total of 18 permutations of the benchmarks.
Eleven different modeling tools are used to compute the benchmark results. The models span a wide range of numerical techniques, including the finite-difference time-domain method, angular spectrum method, pseudospectral method, boundary-element method, and spectral-element method. Good agreement is found between the models, particularly for the position, size, and magnitude of the acoustic focus within the skull.
When comparing results for each model with every other model in a cross-comparison, the median values for each benchmark for the difference in focal pressure and position are less than 10% and 1 mm, respectively. The benchmark definitions, model results, and intercomparison codes are freely available to facilitate further comparisons.
Language: | English |
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Publisher: | Acoustical Society of America |
Year: | 2022 |
Pages: | 1003-1019 |
ISSN: | 15208524 , 00014966 and 01630962 |
Types: | Journal article |
DOI: | 10.1121/10.0013426 |
ORCIDs: | Thielscher, Axel , 0000-0002-0087-8804 and 0000-0001-7782-011X |