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10 items by relevance
1 Book chapter

The Genome of Trichomonas vaginalis

Carlton, Jane M; Malik, Shehre-Banoo; Sullivan, Steven A; Sicheritz-Pontén, Thomas; Tang, Petrus; Hirt, Robert P

Anaerobic Parasitic Protozoa: Genomics and Molecular Biology — 2010

Year: 2010

Language: English

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2 Journal article

Genetic Indicators of Drug Resistance in the Highly Repetitive Genome of Trichomonas vaginalis

Bradic, Martina; Warring, Sally D; Tooley, Grace E; Scheid, Paul; Secor, William E; Land, Kirkwood M; et al. (6 more)

Genome Biology and Evolution — 2017, Volume 9, Issue 6, pp. 1658-1672

Trichomonas vaginalis, the most common nonviral sexually transmitted parasite, causes ∼283 million trichomoniasis infections annually and is associated with pregnancy complications and increased risk of HIV-1 acquisition. The antimicrobial drug metronidazole is used for treatment, but in a fraction

Year: 2017

Language: English

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3 Journal article

Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis

Carlton, Jane M.; Hirt, Robert P.; Silva, Joana C.; Delcher, Arthur L.; Schatz, Michael; Zhao, Qi; et al. (58 more)

Science — 2007, Volume 315, Issue 5809, pp. 207-12

We describe the genome sequence of the protist Trichomonas vaginalis, a sexually transmitted human pathogen. Repeats and transposable elements comprise about two-thirds of the approximately 160-megabase genome, reflecting a recent massive expansion of genetic material. This expansion

Year: 2007

Language: English

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4 Journal article

Massive differential expansion of the Trichomonas vaginalis adaptin genomic complement

DACKS, JOEL B.; CARLTON, JANE; HIRT, ROBERT P.; EMBLEY, T. MARTIN

Journal of Eukaryotic Microbiology — 2005, Volume 52, Issue 2, pp. 7S-27S

Year: 2005

Language: English

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5 Journal article

Getting trichy: tools and approaches to interrogating Trichomonas vaginalis in a post-genome world

Conrad, Melissa D; Bradic, Martina; Warring, Sally D; Gorman, Andrew W; Carlton, Jane M

Trends in Parasitology — 2013, Volume 29, Issue 1, pp. 17-25

Trichomonas vaginalis is a parasite of the urogenital tract in men and women, with a worldwide presence and significant implications for global public health. T. vaginalis research entered the age of genomics with the publication of the first genome sequence in 2007, but subsequent utilization

Year: 2013

Language: English

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6 Journal article

GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis

Aurrecoechea, Cristina; Brestelli, John; Brunk, Brian P.; Carlton, Jane M.; Dommer, Jennifer; Fischer, Steve; et al. (22 more)

Nucleic Acids Research — 2009, Volume 37, Issue Database issue, pp. D526-D530

GiardiaDB (http://GiardiaDB.org) and TrichDB (http://TrichDB.org) house the genome databases for Giardia lamblia and Trichomonas vaginalis, respectively, and represent the latest additions to the EuPathDB (http://EuPathDB.org) family of functional genomic databases. GiardiaDB and TrichDB employ

Year: 2009

Language: Undetermined

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7 Journal article

P4-S3.07 Population genomics of Trichomonas vaginalis reveals a globally distributed two-phylotype population structure

Conrad, M; Gorman, A; Schilinger, J; Sullivan, S; Upcroft, J; Gonzalez, J; et al. (5 more)

Sex Transm Infect — 2011, Volume 87, Issue Suppl_1, pp. A314-A315

OBJECTIVE: Trichomonas vaginalis, the causative agent of human trichomoniasis, is the most prevalent non-viral sexually transmitted infection and has been associated with increased risk of HIV transmission, making detection and treatment a global health priority. In this study, we evaluate the population genomics of globally distributed clinical isolates to characterise genetic diversity and identify population structure. METHODS: We use a panel of 21 microsatellite and three single copy gene markers to evaluate the population genomics of 18 clinical isolates collected from female patients ...

Year: 2011

Language: English

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8 Journal article

P4-S3.07 Population genomics of Trichomonas vaginalis reveals a globally distributed two-phylotype population structure

Conrad, M.; Gorman, A.; Schilinger, J.; Sullivan, S.; Upcroft, J.; Gonzalez, J.; et al. (5 more)

Sexually Transmitted Infections — 2011, Volume 87, Issue Suppl 1, pp. A314-A315

Year: 2011

Language: English

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