Journal article · Conference paper
Packing of protein structures in clusters with magic numbers
Recently we have proposed a model for folding proteins into packed `clusters'. We have constructed a local homology measure for protein fold classes by projecting consecutively secondary structures onto a lattice. Taking into account hydrophobic forces we have found a mechanism for formation of clusters containing magic numbers of secondary structures and multipla of these cluster.
A scheme for the relation between the sequence information and the native fold is given. We have performed a statistical analysis of available protein structures and found agreement with the predicted preferred abundances. In this paper we demonstrate that the results are robust to variations in the coordination number of the model.
Language: | English |
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Publisher: | Springer Berlin Heidelberg |
Year: | 1997 |
Pages: | 236-239 |
Proceedings: | 8th International Symposium on Small Particles and Inorganic Clusters |
ISSN: | 14315866 and 01787683 |
Types: | Journal article and Conference paper |
DOI: | 10.1007/s004600050201 |