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Journal article

The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

By Blin, Kai1,2; Pascal Andreu, Victòria3; de Los Santos, Emmanuel L C4; Del Carratore, Francesco5; Lee, Sang Yup1,2; Medema, Marnix H.3; Weber, Tilmann1,2

From

New Bioactive Compounds, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark1

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark2

Wageningen University & Research3

University of Warwick4

University of Manchester5

Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for the production of these compounds by genome mining. antiSMASH is one of the most popular tools in this field.

The antiSMASH database provides pre-computed antiSMASH results for many publicly available microbial genomes and allows for advanced cross-genome searches. The current version 2 of the antiSMASH database contains annotations for 6200 full bacterial genomes and 18,576 bacterial draft genomes and is available at https://antismash-db.secondarymetabolites.org/.

Language: English
Publisher: Oxford University Press
Year: 2019
Pages: D625-D630
ISSN: 13624962 and 03051048
Types: Journal article
DOI: 10.1093/nar/gky1060
ORCIDs: Blin, Kai , Weber, Tilmann and 0000-0002-2191-2821
Keywords

Databases, Genetic Genome, Bacterial Molecular Sequence Annotation Multigene Family Secondary Metabolism Software

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