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Journal article

Intake of unprocessed and processed meat and the association with cardiovascular disease: An overview of systematic reviews

By Jakobsen, Marianne Uhre1,2; Bysted, Anette1; Mejborn, Heddie1; Stockmarr, Anders3,4; Trolle, Ellen1,5

Edited by Vizcaino, Vicente Martinez

From

National Food Institute, Technical University of Denmark1

Research Group for Risk Benefit, National Food Institute, Technical University of Denmark2

Department of Applied Mathematics and Computer Science, Technical University of Denmark3

Statistics and Data Analysis, Department of Applied Mathematics and Computer Science, Technical University of Denmark4

Research Group for Nutrition, Sustainability and Health Promotion, National Food Institute, Technical University of Denmark5

We conducted an overview of systematic reviews to summarize reviews of cohort studies on intake of unprocessed and processed meat and the risk of cardiovascular disease (CVD), coronary heart disease (CHD), and stroke. Systematic reviews of cohort studies published between January 2010 and August 2020 were identified through a systematic literature search in PubMed, Embase, and Web of Science.

The quality of how each review was conducted was assessed and the overall confidence in the results of each review was rated using AMSTAR 2. The quality of evidence of each meta-analysis was graded using NutriGrade. Three reviews were included, with meta-analyses of unprocessed red meat and CVD (n = 1) and stroke (n = 2); unprocessed poultry and stroke (n = 1); and processed meat and CVD (n = 1), CHD (n = 1), and stroke (n = 3).

The overall confidence in the results of each review was rated as critically low. The meta-evidence was graded moderate for a positive association between unprocessed red meat and stroke and moderate for a positive association between processed meat and CHD and stroke. For other associations the meta-evidence was graded as low or very low.

In conclusion, the associations between unprocessed and processed meat with CVD and major subtypes of CVD have not been extensively investigated.

Language: English
Publisher: MDPI
Year: 2021
Pages: 3303
ISSN: 20726643
Types: Journal article
DOI: 10.3390/nu13103303
ORCIDs: Jakobsen, Marianne Uhre , Bysted, Anette , Mejborn, Heddie , Stockmarr, Anders and Trolle, Ellen
Keywords

Cardiovascular disease Diet Poultry Red meat SDG 3 - Good Health and Well-being Systematic overview

Other keywords

Animals Cardiovascular Diseases Coronary Disease Eating Humans Meat Meta-Analysis as Topic Nutrition. Foods and food supply Stroke Systematic Reviews as Topic TX341-641 cardiovascular disease diet poultry red meat systematic overview

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