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journal:(Biophysical AND Journal) AND title:(Fully AND Streched AND Single AND DNA AND Molecules AND in AND a AND Nanofluidic AND Chip AND Show AND Large-Scale AND Structural AND Variation)

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1 Journal article

Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation

Year: 2013

Language: English

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2 Journal article

Fully Streched Single DNA Molecules in a Nanofluidic Chip Show Large-Scale Structural Variation

reflects the local AT/GC-content. Single molecules are loaded into the chip and imaged. Due to the almost complete stretching of the DNA, structural variations in the size range from kbp to Mbp can be detected and quantified from the melting pattern alone.

Year: 2013

Language: English

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