Journal article
Accelerating the implementation of biocatalysis in industry
PROSYS - Process and Systems Engineering Centre, Department of Chemical and Biochemical Engineering, Technical University of Denmark1
KT Consortium, Department of Chemical and Biochemical Engineering, Technical University of Denmark2
Department of Chemical and Biochemical Engineering, Technical University of Denmark3
Despite enormous progress in protein engineering, complemented by bioprocess engineering, the revolution awaiting the application of biocatalysis in the fine chemical industry has still not been fully realized. In order to achieve that, further research is required on several topics, including (1) rapid methods for protein engineering using machine learning, (2) mathematical modelling of multi-enzyme cascade processes, (3) process standardization, (4) continuous process technology, (5) methods to identify improvements required to achieve industrial implementation, (6) downstream processing, (7) enzyme stability modelling and prediction, as well as (8) new reactor technology.
In this brief mini-review, the status of each of these topics will be briefly discussed.
| Language: | English |
|---|---|
| Publisher: | Springer Berlin Heidelberg |
| Year: | 2019 |
| Pages: | 4733-4739 |
| ISSN: | 14320614 and 01757598 |
| Types: | Journal article |
| DOI: | 10.1007/s00253-019-09796-x |
| ORCIDs: | Woodley, John M. |
