Journal article
Methods for selection of aptamers to protein targets
Institute of Molecular Genetics, Russian Academy of Sciences, pl. Kurchatova 2, 123182 Moscow, Russia. akulb@img.ras.ru1
Aptamers are synthetic single-stranded RNA or DNA molecules capable of specific binding to other target molecules. In this review, the main aptamer properties are considered and methods for selection of aptamers against various protein targets are described. Special attention is given to the methods for directed selection of aptamers, which allow one to obtain ligands with specified properties.
| Language: | English |
|---|---|
| Publisher: | Nauka/Interperiodica |
| Year: | 2007 |
| Pages: | 1505-1518 |
| ISSN: | 16083040 and 00062979 |
| Types: | Journal article |
| DOI: | 10.1134/s000629790713007x |
Aptamers, Nucleotide Biochemistry, general Biomedicine general Bioorganic Chemistry Combinatorial Chemistry Techniques DNA, Single-Stranded Epitopes Gene Library Genetic Techniques Life Sciences Ligands Microbiology Oligonucleotides Proteins RNA SELEX SELEX Aptamer Technique Selection, Genetic aptamers aptazymes site-directed selection
