Journal article
Convergent synthesis of PAMAM dendrimers using click chemistry of azide-functionalized PAMAM dendrons
Department of Chemistry, Dong-A University, Hadan-2-dong, Busan 604-714, Republic of Korea1
Department of Chemical and Biochemical Engineering, Dongguk University, Seoul 100-715, Republic of Korea2
Department of Chemistry Education and Center for Plastic Information System, Pusan National University, Busan 609-735, Republic of Korea3
Azide-functionalized PAMAM dendrons containing an azidopropylamine focal point were synthesized by the divergent method and applied for the construction of symmetric PAMAM-like dendrimers containing 1,2,3-triazole rings as connectors via stitching with two different multi-terminal alkynes. The stitching method was based on the click chemistry protocol, i.e., the copper-catalyzed cycloaddition reaction between an alkyne and an azide.
| Language: | English |
|---|---|
| Year: | 2006 |
| Pages: | 9193-9200 |
| ISSN: | 14645416 and 00404020 |
| Types: | Journal article |
| DOI: | 10.1016/j.tet.2006.07.030 |
