Journal article
Acoustofluidics 12: Biocompatibility and cell viability in microfluidic acoustic resonators
Department of Applied Physics, Royal Institute of Technology, SE-10691, Stockholm, Sweden. martin@biox.kth.se1
Manipulation of biological cells by acoustic radiation forces is often motivated by its improved biocompatibility relative to alternative available methods. On the other hand, it is well known that acoustic exposure is capable of causing damage to tissue or cells, primarily due to heating or cavitation effects.
Therefore, it is important to define safety guidelines for the design and operation of the utilized devices. This tutorial discusses the biocompatibility of devices designed for acoustic manipulation of mammalian cells, and different methods for quantifying the cell viability in such devices.
Language: | English |
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Publisher: | The Royal Society of Chemistry |
Year: | 2012 |
Pages: | 2018-2028 |
ISSN: | 14730189 and 14730197 |
Types: | Journal article |
DOI: | 10.1039/c2lc40201g |