Journal article
Application of SNPs for population genetics of nonmodel organisms: new opportunities and challenges : ANALYTICAL APPROACHES
Bangor University1
Section for Population Ecology and Genetics, National Institute of Aquatic Resources, Technical University of Denmark2
National Institute of Aquatic Resources, Technical University of Denmark3
Royal Zoological Society of Scotland4
University of Bologna5
Stichting Katholieke Universiteit6
Section for Marine Living Resources, National Institute of Aquatic Resources, Technical University of Denmark7
Recent improvements in the speed, cost and accuracy of next generation sequencing are revolutionizing the discovery of single nucleotide polymorphisms (SNPs). SNPs are increasingly being used as an addition to the molecular ecology toolkit in nonmodel organisms, but their efficient use remains challenging.
Here, we discuss common issues when employing SNP markers, including the high numbers of markers typically employed, the effects of ascertainment bias and the inclusion of nonneutral loci in a marker panel. We provide a critique of considerations specifically associated with the application and population genetic analysis of SNPs in nonmodel taxa, focusing specifically on some of the most commonly applied methods.
Language: | English |
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Year: | 2011 |
Pages: | 123-136 |
ISSN: | 17550998 and 1755098x |
Types: | Journal article |
DOI: | 10.1111/j.1755-0998.2010.02943.x |
ORCIDs: | Hansen, Jakob Hemmer , Bekkevold, Dorte and Eg Nielsen, Einar |