Journal article
BacHBerry:: BACterial Hosts for production of Bioactive phenolics from bERRY fruits
Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark1
Jülich Research Centre2
Biotempo3
University of Minho4
John Innes Centre5
The James Hutton Institute6
Chr. Hansen AS7
University of Lisbon8
University of Edinburgh9
CAS - Institute of Botany10
Biofaction KG11
Research Groups, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark12
University of Groningen13
Delft University of Technology14
N.I.Vavilov Research Institute of Plant Industry15
Applied Metabolic Engineering, Research Groups, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark16
Heriot-Watt University17
Centrum voor Wiskunde en Informatica18
Microbial Evolution and Synthetic Biology, Research Groups, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark19
Instituto de Biologia Experimental e Tecnológica20
NOVA University Lisbon21
Institut national de recherche en informatique et en automatique22
Pontificia Universidad Católica de Chile23
Evolva SA24
University of Copenhagen25
...and 15 moreBACterial Hosts for production of Bioactive phenolics from bERRY fruits (BacHBerry) was a 3-year project funded by the Seventh Framework Programme (FP7) of the European Union that ran between November 2013 and October 2016. The overall aim of the project was to establish a sustainable and economically-feasible strategy for the production of novel high-value phenolic compounds isolated from berry fruits using bacterial platforms.
The project aimed at covering all stages of the discovery and pre-commercialization process, including berry collection, screening and characterization of their bioactive components, identification and functional characterization of the corresponding biosynthetic pathways, and construction of Gram-positive bacterial cell factories producing phenolic compounds.
Further activities included optimization of polyphenol extraction methods from bacterial cultures, scale-up of production by fermentation up to pilot scale, as well as societal and economic analyses of the processes. This review article summarizes some of the key findings obtained throughout the duration of the project.
| Language: | English |
|---|---|
| Publisher: | Springer Netherlands |
| Year: | 2018 |
| Pages: | 291-326 |
| Journal subtitle: | Fundamentals and Perspectives of Natural Products Research |
| ISSN: | 1572980x and 15687767 |
| Types: | Journal article |
| DOI: | 10.1007/s11101-017-9532-2 |
| ORCIDs: | Dudnik, Alexey , 0000-0002-9448-0652 , 0000-0001-5513-3730 , 0000-0002-7937-8027 , Forster, Jochen , 0000-0002-6865-8058 , 0000-0002-4701-8254 , 0000-0003-4925-6923 , 0000-0001-5596-7735 , Ferro, Roberto , Nørholm, Morten H.H. and 0000-0003-1249-1807 |
