Journal article
Parabolic section and distance excess of space curves applied to protein structure classification
Proteins are long chain molecules that fold up into beautiful and complicated three-dimensional structures before fulfilling their biological functions in the living organisms. With the aim of providing an efficient tool for describing the proteins' native folds, we present a global geometric measure of a space curve.
This geometric measure allows us to define descriptors of protein structures that quantify how parallel the secondary structure elements of a protein are. These descriptors are C-2 in deformations of the protein structure, are evaluated very fast and reliably, and are demonstrated to capture essential parts of the protein native fold universe.
Language: | English |
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Publisher: | Springer Netherlands |
Year: | 2008 |
Pages: | 91-107 |
ISSN: | 15729168 and 00465755 |
Types: | Journal article |
DOI: | 10.1007/s10711-008-9247-z |
ORCIDs: | Røgen, Peter |