Journal article
Optimized microwave delivery in dDNP
Dissolution dynamic nuclear polarization (dDNP) has permitted the production of highly polarized liquid-state samples enabling real-time imaging of metabolic processes non-invasively in vivo. The desire for higher magnetic resonance sensitivity has led to the development of multiple home-built and commercial dDNP polarizers employing solid-state microwave sources.
Providing efficient microwave delivery that avoids unwanted heating of the sample is a crucial step to achieve high nuclear polarization. Consequently, a process is described to reduce waveguide attenuation due to resistive loss thereby doubling the delivered power. A mirror and reflector are designed and tested to increase the microwave field density across the sample volume resulting in a 2.3 dB increase of delivered power.
Thermal considerations with regards to waveguide geometry and dDNP probe design are discussed. A thermal model of the dDNP probe is computed and experimentally verified.
Language: | English |
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Year: | 2019 |
Pages: | 58-65 |
ISSN: | 10960856 and 10907807 |
Types: | Journal article |
DOI: | 10.1016/j.jmr.2019.06.004 |
ORCIDs: | Albannay, Mohammed M. , M.O. Vinther, Joachim , Capozzi, Andrea , Zhurbenko, Vitaliy and Ardenkjær-Larsen, Jan Henrik |