Journal article
Novel 3D microelectrodes and pipettes by wet and dry etching
Department of Micro- and Nanotechnology, Technical University of Denmark1
Nano Bio Integrated Systems, Department of Micro- and Nanotechnology, Technical University of Denmark2
University College Cork3
Technical University of Denmark4
Polymer Microsystems for Cell Processing, Department of Micro- and Nanotechnology, Technical University of Denmark5
The purpose of this work is to develop novel 3D micro- and nanoelectrodes and pipettes by use of carefully optimised standard microfabrication techniques such as wet (by KOH) and dry silicon etching. Two types of electrodes have been fabricated and characterized: small nanoelectrodes to be used for localised measurements on cell cultures and high aspect ratio scalloped microelectrodes for measurements in brain slices.
This paper presents improved fabrication processes for both types of electrodes and the pipettes, as well as the electrical and electrochemical characterization of the small electrodes in order to confirm their functionality. Although functional, an increase in the electrode surface area is needed if they are to be used for electrophysiological measurements.
Finally, the pipettes fabricated have openings of the order of 500nm, which makes them ideal candidates for localised stimulation of cell or brain slice cultures.
Language: | English |
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Year: | 2012 |
Pages: | 33-36 |
ISSN: | 18735568 and 01679317 |
Types: | Journal article |
DOI: | 10.1016/j.mee.2012.07.115 |
ORCIDs: | Dimaki, Maria , Olsen, Mark H. and Svendsen, Winnie E. |