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Journal article

In Vivo Phenotyping of Tumor Metabolism in a Canine Cancer Patient with Simultaneous (18)F-FDG-PET and Hyperpolarized (13)C-Pyruvate Magnetic Resonance Spectroscopic Imaging (hyperPET): Mismatch Demonstrates that FDG may not Always Reflect the Warburg Effect

By Gutte, Henrik1; Hansen, Adam E1; Larsen, Majbrit M E1; Rahbek, Sofie1; Johannesen, Helle H1; Ardenkjær-Larsen, Jan Henrik2,3,4; Kristensen, Annemarie T1; Højgaard, Liselotte1; Kjær, Andreas1

Edited by Jackson, Graham

From

University of Copenhagen1

Center for Hyperpolarization in Magnetic Resonance, Centers, Technical University of Denmark2

Department of Electrical Engineering, Technical University of Denmark3

Center for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark4

In this communication the mismatch between simultaneous (18)F-FDG-PET and a (13)C-lactate imaging (hyperPET) in a biopsy verified squamous cell carcinoma in the right tonsil of a canine cancer patient is shown. The results demonstrate that (18)F-FDG-PET may not always reflect the Warburg effect in all tumors.

Language: English
Publisher: MDPI
Year: 2015
Pages: 287-289
ISSN: 20754418
Types: Journal article
DOI: 10.3390/diagnostics5030287
ORCIDs: Ardenkjær-Larsen, Jan Henrik and 0000-0002-2706-5547
Keywords

13C-pyruvate 18F-FDG-PET Cancer Dynamic nuclear polarization HyperPET Hyperpolarized MR Molecular imaging PET/MR SDG 3 - Good Health and Well-being

Other keywords

Medicine (General) R5-920 cancer dynamic nuclear polarization hyperPET hyperpolarized molecular imaging

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