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Journal article

Metabolite Depletion Affects Flux Profiling of Cell Lines

By Nilsson, A.1; Haanstra, J. R.2; Teusink, B.2; Nielsen, J.3,4

From

Chalmers University of Technology1

Vrije Universiteit Amsterdam2

Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark3

Yeast Cell Factories, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark4

Quantifying the rate of consumption and release of metabolites (i.e., flux profiling) has become integral to the study of cancer. The fluxes as well as the growth of the cells may be affected by metabolite depletion during cultivation.

Language: English
Year: 2018
Pages: 395-397
ISSN: 13624326 , 09680004 and 01677640
Types: Journal article
DOI: 10.1016/j.tibs.2018.03.009
Keywords

Cancer Glutamine Metabolic modeling SDG 3 - Good Health and Well-being Serine

Other keywords

Cell Culture Techniques Humans Neoplasms Tumor Cells, Cultured cancer glutamine metabolic modeling serine

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