Journal article
Interfacial electrochemical electron transfer in biology – Towards the level of the single molecule
Physical electrochemistry has undergone a remarkable evolution over the last few decades, integrating advanced techniques and theory from solid state and surface physics. Single-crystal electrode surfaces have been a core notion, opening for scanning tunnelling microscopy directly in aqueous electrolyte (in situ STM).
Interfacial electrochemistry of metalloproteins is presently going through a similar transition. Electrochemical surfaces with thiol-based promoter molecular monolayers (SAMs) as biomolecular electrochemical environments and the biomolecules themselves have been mapped with unprecedented resolution, opening a new area of single-molecule bioelectrochemistry.
We consider first in situ STM of small redox molecules, followed by in situ STM of thiol-based SAMs as molecular views of bioelectrochemical environments. We then address electron transfer metalloproteins, and multi-centre metalloenzymes including applied single-biomolecular perspectives based on metalloprotein/metallic nanoparticle hybrids.
Language: | English |
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Year: | 2012 |
Pages: | 526-535 |
ISSN: | 18733468 and 00145793 |
Types: | Journal article |
DOI: | 10.1016/j.febslet.2011.10.023 |
ORCIDs: | Zhang, Jingdong and Chi, Qijin |