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Journal article

Localized biosensing with Topas microstructured Polymer Optical Fiber

By Emiliyanov, Grigoriy Andreev1,2; Jensen, Jesper Bo2; Bang, Ole1,2; Bjarklev, Anders Overgaard2; Hoiby, Poul E.3; Pedersen, Lars H.3; Kjær, Erik Michael4; Lindvold, Lars

From

Fibers & Nonlinear Optics, Department of Photonics Engineering, Technical University of Denmark1

Department of Photonics Engineering, Technical University of Denmark2

Bioneer A/S3

Department of Management Engineering, Technical University of Denmark4

We present what is believed to be the first microstructured polymer optical fiber (mPOF) fabricated from Topas cyclic olefin copolymer, which has attractive material and biochemical properties. This polymer allows for a novel type of fiber-optic biosensor, where localized sensor layers may be activated on the inner side of the air holes in a predetermined section of the mPOF.

The concept is demonstrated using a fluorescencebased method for selective detection of fluorophore-labeled antibodies. © 2007 Optical Society of America

Language: English
Year: 2007
Pages: 460-462
ISSN: 01469592 and 15394794
Types: Journal article
DOI: 10.1364/OL.32.000460
ORCIDs: Bang, Ole and Lindvold, Lars
Keywords

Alkenes Biocompatible Materials Biosensing Techniques C-Reactive Protein Carbocyanines Fiber Optic Technology Microscopy, Fluorescence Optical Fibers Optics and Photonics Polymers Polymethyl Methacrylate Streptavidin Ultraviolet Rays cyanine dye 3

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