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Journal article

Monitoring and control of microbioreactors: An expert opinion on development needs

From

Department of Chemical and Biochemical Engineering, Technical University of Denmark1

StemCell Systems GmbH2

Linköping University3

Center for Process Engineering and Technology, Department of Chemical and Biochemical Engineering, Technical University of Denmark4

University College London5

Technical University of Braunschweig6

m2p-labs GmbH7

Charité – Universitätsmedizin Berlin8

Technical University of Berlin9

Novo Nordisk Foundation10

TU Dortmund University11

...and 1 more

This perspective article is based on an expert panel review on microbioreactor applications in biochemical and biomedical engineering that was organized by the M3C (measurement, monitoring, modelling and control) Working Group of the European Section of Biochemical Engineering Science (ESBES) in the European Federation of Biotechnology (EFB).

The aim of the panel was to provide an updated view on the present status of the subject and to identify critical needs and issues for furthering the successful development of microbioreactor monitoring and control. This will benefit future bioprocess development and in vitro toxicity testing. The article concludes with a set of recommendations for extended use and further development of microbioreactors.

Language: English
Year: 2012
Pages: 1308-1314
ISSN: 18607314 and 18606768
Types: Journal article
DOI: 10.1002/biot.201200157
ORCIDs: Gernaey, Krist and Krühne, Ulrich

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