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Journal article

Cantilever biosensor reader using a common-path, holographic optical interferometer

From

Optical Microsensors and Micromaterials, Department of Photonics Engineering, Technical University of Denmark1

Department of Photonics Engineering, Technical University of Denmark2

Optical Sensor Technology, Department of Photonics Engineering, Technical University of Denmark3

Diode Lasers and LED Systems, Department of Photonics Engineering, Technical University of Denmark4

Unisensor A/S5

We demonstrate an optical reader principle aimed at monitoring biologically induced deflections of microcantilevers often used in biosensor systems. The principle is based on a so-called common-path optical interferometer in which the two interfering optical beams are copropagating,which makes the system less sensitive to external disturbances.

A detection limit of around 1 nm’s deflection is demonstrated.

Language: English
Publisher: American Institute of Physics
Year: 2010
ISSN: 10773118 and 00036951
Types: Journal article
DOI: 10.1063/1.3522888
ORCIDs: Pedersen, Henrik Chresten , Jakobsen, Michael Linde , Hanson, Steen Grüner and Dam-Hansen, Carsten

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