Journal article
Cantilever biosensor reader using a common-path, holographic optical interferometer
Optical Microsensors and Micromaterials, Department of Photonics Engineering, Technical University of Denmark1
Department of Photonics Engineering, Technical University of Denmark2
Optical Sensor Technology, Department of Photonics Engineering, Technical University of Denmark3
Diode Lasers and LED Systems, Department of Photonics Engineering, Technical University of Denmark4
Unisensor A/S5
We demonstrate an optical reader principle aimed at monitoring biologically induced deflections of microcantilevers often used in biosensor systems. The principle is based on a so-called common-path optical interferometer in which the two interfering optical beams are copropagating,which makes the system less sensitive to external disturbances.
A detection limit of around 1 nm’s deflection is demonstrated.
Language: | English |
---|---|
Publisher: | American Institute of Physics |
Year: | 2010 |
ISSN: | 10773118 and 00036951 |
Types: | Journal article |
DOI: | 10.1063/1.3522888 |
ORCIDs: | Pedersen, Henrik Chresten , Jakobsen, Michael Linde , Hanson, Steen Grüner and Dam-Hansen, Carsten |