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Journal article

Fimbrial adhesins from extraintestinal Escherichia coli : ExPEC fimbriae

From

Division of Microbiology and Risk Assessment, National Food Institute, Technical University of Denmark1

National Food Institute, Technical University of Denmark2

Extraintestinal pathogenic Escherichia coli (ExPEC) represent an important subclass of E. coli that cause a wide spectrum of diseases in human and animal hosts. Fimbriae are key virulence factors of ExPEC strains. These long surface located rod-shaped organelles mediate receptor-specific attachment to host tissue surfaces (tissue tropism).

Some ExPEC fimbriae have additional functions such as the promotion of biofilm formation, cell aggregation and adherence to abiotic surfaces. Here we review the structure, function and contribution to virulence of fimbriae associated with ExPEC strains.

Language: English
Year: 2010
Pages: 628-640
ISSN: 17582229
Types: Journal article
DOI: 10.1111/j.1758-2229.2010.00166.x

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