Journal article
Nonlinear Denoising and Analysis of Neuroimages With Kernel Principal Component Analysis and Pre-Image Estimation
We investigate the use of kernel principal component analysis (PCA) and the inverse problem known as pre-image estimation in neuroimaging: i) We explore kernel PCA and pre-image estimation as a means for image denoising as part of the image preprocessing pipeline. Evaluation of the denoising procedure is performed within a data-driven split-half evaluation framework. ii) We introduce manifold navigation for exploration of a nonlinear data manifold, and illustrate how pre-image estimation can be used to generate brain maps in the continuum between experimentally defined brain states/classes.
We base these illustrations on two fMRI BOLD data sets — one from a simple finger tapping experiment and the other from an experiment on object recognition in the ventral temporal lobe.
Language: | English |
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Year: | 2012 |
Pages: | 1807-1818 |
ISSN: | 10959572 and 10538119 |
Types: | Journal article |
DOI: | 10.1016/j.neuroimage.2012.01.096 |
ORCIDs: | Madsen, Kristoffer Hougaard and Hansen, Lars Kai |
Classification Decoding Kernel PCA Multivariate analysis NPAIRS resampling Nonlinear modeling Pre-image estimation
Algorithms Artifacts Cerebral Cortex Evoked Potentials Functional Neuroimaging Humans Image Enhancement Image Interpretation, Computer-Assisted Magnetic Resonance Imaging Nonlinear Dynamics Pattern Recognition, Automated Principal Component Analysis Reproducibility of Results Sensitivity and Specificity Signal-To-Noise Ratio