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Journal article

MR spectroscopy of hepatic fat and adiponectin and leptin levels during testosterone therapy in type 2 diabetes: a randomized, double-blinded, placebo-controlled trial: A randomized, double-blinded, placebo-controlled trial

By Magnussen, L V1; Andersen, P E1; Diaz, Alejandro Rafael1; Ostojic, J2; Højlund, K.1; Hougaard, D. M.3; Christensen, Anders Nymark4,5; Nielsen, T. L.1; Andersen, M1

From

University of Southern Denmark1

University of Novi Sad2

Statens Serum Institut3

Department of Applied Mathematics and Computer Science, Technical University of Denmark4

Visual Computing, Department of Applied Mathematics and Computer Science, Technical University of Denmark5

Men with type 2 diabetes mellitus (T2D) often have lowered testosterone levels and an increased risk of cardiovascular disease (CVD). Ectopic fat increases the risk of CVD, whereas subcutaneous gluteofemoral fat protects against CVD and has a beneficial adipokine-secreting profile. Testosterone replacement therapy (TRT) may reduce the content of ectopic fat and improve the adipokine profile in men with T2D.

A randomized, double-blinded, placebo-controlled study in 39 men aged 50-70 years with T2D and bioavailable testosterone levels

Language: English
Publisher: European Federation of Endocrine Societies
Year: 2017
Pages: 157-168
ISSN: 1479683x and 08044643
Types: Journal article
DOI: 10.1530/EJE-17-0071
ORCIDs: Christensen, Anders Nymark
Keywords

SDG 3 - Good Health and Well-being

Other keywords

ADIPOQ protein, human Adiponectin Aged Diabetes Mellitus, Type 2 Double-Blind Method Hormone Replacement Therapy Humans Leptin Liver Magnetic Resonance Spectroscopy Male Middle Aged Testosterone

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