Journal article
[18F]Fluoride recovery via gaseous [18F]HF
Biomedical Tracers, Radiation Research Division, Risø National Laboratory for Sustainable Energy, Technical University of Denmark1
Radiation Research Division, Risø National Laboratory for Sustainable Energy, Technical University of Denmark2
Risø National Laboratory for Sustainable Energy, Technical University of Denmark3
Acidification of target water with H2SO4 in a specially constructed glassy carbon/polyethylene apparatus allowed for recovery of up to 82% of [18F]fluoride as [18F]HF gas. The [18F]HF distillate was found to be acid-free but moist; when passed through a solution of tBuPh2SiOTf, it yielded [18F]tBuPh2SiF.
The multivariate design of experiment showed that the key to high yield of [18F]HF was the efficient degassing of the reaction mixture.
| Language: | English |
|---|---|
| Year: | 2011 |
| Pages: | 816-818 |
| ISSN: | 03624803 and 10991344 |
| Types: | Journal article |
| DOI: | 10.1002/jlcr.1931 |
| ORCIDs: | Jensen, Mikael and Zhuravlev, Fedor |
