Journal article
Prevalence of Antibodies Against Foot-and-Mouth Disease Virus in Cattle in Kasese and Bushenyi Districts in Uganda
Makerere University1
Ministry of Agriculture, Animal Industry and Fisheries2
National Veterinary Institute, Technical University of Denmark3
Sektion for Eksotiske Virussygdomme, Division of Virology, National Veterinary Institute, Technical University of Denmark4
Division of Virology, National Veterinary Institute, Technical University of Denmark5
Abstract: The aim of this study was to determine the seroprevalence and serotype-specificity of the circulating antibodies against Foot-and-Mouth Disease Virus (FMDV) in cattle in K asese and Bushenyi districts in Uganda. A total of 309 serum samples were collected and tested for antibodies against Non-Structural (NS) and Structural Proteins (SP) using Ceditest® FMDV-NS and C editest® FMDV type O test kits.
Seroprevalences were much higher in Kasese in both tests (61 and 43%, respectively) than in Bushenyi (3 and 4% , respectively). A high proportion of sera, that tested positive in the NSP test, were subjected to seven serotype specific blocking ELISAs for antibodies against the seven FMDV serotypes (O, A, C, Asia 1, SAT 1, SAT 2 and SAT 3).
The study showed presence of antibodies against four FMDV serotypes with decreasing magnitude as follows: O> SAT 1> SAT 3/SAT 2. It is recommended to develop sampling schemes to include virus recovery and identification, as well as to focus serum sampling on young unvaccinated stock.
Language: | English |
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Year: | 2010 |
Pages: | 89-96 |
ISSN: | 20412908 and 20412894 |
Types: | Journal article |