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Journal article

Inter-individual variation, seasonal variation and close correlation of OGG1 and ERCC1 mRNA levels in full blood from healthy volunteers

From

Division of Toxicology and Risk Assessment, National Food Institute, Technical University of Denmark1

National Food Institute, Technical University of Denmark2

Stald/vægterservice, Division of Virology, National Veterinary Institute, Technical University of Denmark3

Division of Virology, National Veterinary Institute, Technical University of Denmark4

National Veterinary Institute, Technical University of Denmark5

Technical University of Denmark6

The mRNA levels of the nucleotide excision DNA repair gene ERCC1 and the base excision DNA repair gene OGG1 were quantified in 43 healthy volunteers in a dietary intervention trial as markers for the DNA repair capacity. Nine samples were collected from each subject over a period of 52 days. Sampling took place from January to May.

The mRNA levels of OGG1 and ERCC1 correlated closely (r = 0.86, P

Language: English
Year: 2002
Pages: 1505-1509
ISSN: 14602180 and 01433334
Types: Journal article
DOI: 10.1093/carcin/23.9.1505
ORCIDs: 0000-0002-2021-1249 and 0000-0001-9552-8518

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