Journal article
Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs
Adaptive Immunology & Parasitology, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark1
Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark2
National Veterinary Institute, Technical University of Denmark3
Secretariat, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark4
Section for Veterinary Diagnostics, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark5
False-positive serological reactions (FPSR) due to infections with Yersinia enterocolitica serotype 0: 9 (YeO:9) are a problem in tests for brucellosis. In the present study, FPSR in classical and novel tests for brucellosis following experimental infections of pigs with YeO:9 were compared with responses of B. suis biovar 2-inoculated pigs.
FPSR were limited to 2-9 weeks post-YeO:9 inoculation, while B. suis-infected pigs were test-positive throughout the 21-week period of investigation. Although YeO:9-inoculated pigs exhibited FPSR in Brucella tests for a limited period of time, the serological responses in a YeO:9-purified O-antigen indirect ELISA did not decrease accordingly.
Analysis of available cross-sectional serum samples from pig herds naturally infected with YeO: 9 or B. suis biovar 2 confirmed that the observed difference in the duration of the serological responses between the two infections could be used to discriminate between herds infected with B. suis biovar 2 and YeO:9.
| Language: | English |
|---|---|
| Publisher: | Cambridge University Press |
| Year: | 2006 |
| Pages: | 347-357 |
| ISSN: | 14694409 and 09502688 |
| Types: | Journal article |
| DOI: | 10.1017/S095026880500511X |
| ORCIDs: | Jungersen, Gregers |
