Journal article
The strength of intron donor splice sites in human genes displays a bell-shaped pattern
Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, DK-2800 Lyngby, Denmark1
Motivation: The gene concept has recently changed from the classical one protein notion into a much more diverse picture, where overlapping or fused transcripts, alternative transcription initiation, and genes within genes, add to the complexity generated by alternative splicing. Increased understanding of the mechanisms controlling pre-mRNA splicing is thus important for a wide range of aspects relating to gene expression.
Language: | Undetermined |
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Publisher: | Oxford University Press |
Year: | 2011 |
Pages: | 3079-3084 |
ISSN: | 13674811 , 14602059 and 13674803 |
Types: | Journal article |
DOI: | 10.1093/bioinformatics/btr532 |