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Journal article · Ahead of Print article

Detection of Paroxysms in Long-Term, Single Channel EEG-Monitoring of Patients with Typical Absence Seizures

From

Copenhagen University Hospital Herlev and Gentofte1

Copenhagen Center for Health Technology, Centers, Technical University of Denmark2

Department of Electrical Engineering, Technical University of Denmark3

Biomedical Engineering, Department of Electrical Engineering, Technical University of Denmark4

North Zealand Hospital5

Absence seizures are associated with generalized 2.5-5 Hz spike-wave discharges in the EEG. Rarely are patients, parents or physicians aware of duration or incidence of seizures. Six patients were monitored with a portable EEG-device over four times 24 hours to evaluate how easily outpatients are monitored and how well an automatic seizure detection algorithm can identify the absences.

Based on patient-specific modeling, we achieved a sensitivity of 98.4% with only 0.23 false detections per hour. This yields a clinically satisfying performance with a positive predictive value of 87.1%. Portable EEG-recorders identifying paroxystic events in epilepsy outpatients are a promising tool for patients and physicians dealing with absence epilepsy.

Albeit the small size of the EEG-device, some children still complained about the obtrusive nature of the device. We aim at developing less obtrusive though still very efficient devices e.g. hidden in the ear canal or below the skin.

Language: English
Publisher: IEEE
Year: 2017
Pages: 2000108
ISSN: 21682372
Types: Journal article and Ahead of Print article
DOI: 10.1109/JTEHM.2017.2649491
ORCIDs: Sørensen, Helge Bjarup Dissing

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