Journal article
Source attribution of human salmonellosis using a meta-analysis of case-control studies of sporadic infections
Division of Epidemiology and Microbial Genomics, National Food Institute, Technical University of Denmark1
National Food Institute, Technical University of Denmark2
Division of Microbiology and Risk Assessment, National Food Institute, Technical University of Denmark3
Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark4
National Veterinary Institute, Technical University of Denmark5
Section for Veterinary Epidemiology and public sector consultancy, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark6
Salmonella is an important cause of human illness. Disease is frequently associated with foodborne transmission, but other routes of exposure are recognized. Identifying sources of disease is essential for prioritizing public health interventions. Numerous case-control studies of sporadic salmonellosis have been published, often using different methodologies and settings.
Systematic reviews consist of a formal process for literature review focused on a research question. With the objective of identifying the most important risk factors for salmonellosis, we performed a systematic review of case-control studies and a meta-analysis of obtained results. Thirty-five Salmonella case-control studies were identified.
In the meta-analysis, heterogeneity between studies and possible sources of bias were investigated, and pooled odds ratios estimated. Results suggested that travel, predisposing factors, eating raw eggs, and eating in restaurants were the most important risk factors for salmonellosis. Sub-analyses by serotype were performed when enough studies were available.
Language: | English |
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Publisher: | Cambridge University Press |
Year: | 2012 |
Pages: | 959-969 |
ISSN: | 14694409 and 09502688 |
Types: | Journal article |
DOI: | 10.1017/S0950268811002172 |
ORCIDs: | 0000-0003-1112-0254 , Pires, Sara Monteiro and Hald, Tine |