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Journal article

Polycyclic alkaloids via transannular Mannich reactions

By Vital, Paulo1; Hosseini, Masood1; Shanmugham, M. S.; Gotfredsen, Charlotte Held1,2; Harris, Pernille1,3; Tanner, David Ackland1,2

From

Department of Chemistry, Technical University of Denmark1

Organic Chemistry, Department of Chemistry, Technical University of Denmark2

X-ray Crystallography, Department of Chemistry, Technical University of Denmark3

The tricyclic compound 13, representing the framework of the cylindricine 4 and lepadiformine 5 alkaloids, was prepared in a single operation via the first example of a transannular Mannich reaction involving a macrocyclic diketoamine 12.

Language: English
Publisher: The Royal Society of Chemistry
Year: 2009
Pages: 1888-1890
ISSN: 1364548x and 13597345
Types: Journal article
DOI: 10.1039/b822955d
ORCIDs: Gotfredsen, Charlotte Held , Harris, Pernille and Tanner, David Ackland

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