Journal article
Polymer photonic crystal dye lasers as optofluidic cell sensors
NSE-Optofluidics Group, NanoSystemsEngineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark1
NanoSystemsEngineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark2
Department of Micro- and Nanotechnology, Technical University of Denmark3
Fluidic Array Systems and Technology Group, Biomedical Micro Systems Section, Department of Micro- and Nanotechnology, Technical University of Denmark4
Biomedical Micro Systems Section, Department of Micro- and Nanotechnology, Technical University of Denmark5
Surface Engineering Group, Polymer Micro and Nano Engineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark6
Polymer Micro and Nano Engineering Section, Department of Micro- and Nanotechnology, Technical University of Denmark7
Structured Electromagnetic Materials, Department of Photonics Engineering, Technical University of Denmark8
Department of Photonics Engineering, Technical University of Denmark9
Dye doped hybrid polymer lasers are implemented as label free evanescent field biosensors for detection of cells. It is demonstrated that although the coverage is irregular and the cells extend over several lattice constants, the emission wavelength depends linearly on the fraction of the surface covered by the HeLa cells used as model system.
Design parameters relating to photonic crystal sensing of large objects are identified and discussed. The lasers are chemically modified to bind cells and molecules with flexible UV activated linker molecules.
| Language: | English |
|---|---|
| Publisher: | The Optical Society |
| Year: | 2009 |
| Pages: | 2722-2730 |
| ISSN: | 10944087 |
| Types: | Journal article |
| DOI: | 10.1364/OE.17.002722 |
| ORCIDs: | Jakobsen, Mogens Havsteen , Mortensen, Niels Asger , Dufva, Hans Martin and Kristensen, Anders |
