Journal article
Brachyspira murdochii colitis in pigs
Section for Veterinary Diagnostics, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark1
Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark2
National Veterinary Institute, Technical University of Denmark3
Microbial Ecology, Division of Veterinary Diagnostics and Research, National Veterinary Institute, Technical University of Denmark4
The weakly beta-hemolytic porcine spirochete Brachyspira murdochii is considered a normal intestinal commensal. In the present study, however, a field case of B murdochii–associated catarrhal colitis was identified in a pig, as characterized by extensive spirochetal colonization of the surface epithelium.
Experimentally, 8 weaned pigs were challenged with the B murdochii isolate, reproducing catarrhal colitis in 2 animals. By applying fluorescent in situ hybridization using a species-specific oligonucleotide probe targeting 23S rRNA, B murdochii organisms were found in high numbers and were closely associated with the surface epithelium in the pigs with catarrhal colitis.
The results indicate that, when present in high numbers, B murdochii is low pathogenic for pigs.
Language: | English |
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Publisher: | SAGE Publications |
Year: | 2010 |
Pages: | 334-338 |
ISSN: | 01913808 , 03009858 and 15442217 |
Types: | Journal article |
DOI: | 10.1177/0300985809359054 |
ORCIDs: | Jensen, Tim Kåre and Boye, Mette |