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Journal article

Complement-mediated tumour growth: implications for cancer nanotechnology and nanomedicines

By Moghimi, S. M.; Andresen, Thomas Lars1,2,3

From

Colloids and Biological Interfaces Group, Self-organizing materials for nanotechnology Section, Department of Micro- and Nanotechnology, Technical University of Denmark1

Self-organizing materials for nanotechnology Section, Department of Micro- and Nanotechnology, Technical University of Denmark2

Department of Micro- and Nanotechnology, Technical University of Denmark3

The recent unexpected observation that complement activation helps turnout growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.

Language: English
Year: 2009
Pages: 1571-1572
ISSN: 18729142 and 01615890
Types: Journal article
DOI: 10.1016/j.molimm.2009.02.014
ORCIDs: Andresen, Thomas Lars
Keywords

C5a Cancer Complement system Nanoparticles SDG 3 - Good Health and Well-being

Other keywords

Cell Growth Processes Complement System Proteins Disease Progression Former Faculty of Pharmaceutical Sciences Humans Nanomedicine Nanotechnology Neoplasms

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