Conference paper
Segmenting Multiple Sclerosis Lesions using a Spatially Constrained K-Nearest Neighbour approach
We propose a method for the segmentation of Multiple Sclerosis lesions. The method is based on probability maps derived from a K-Nearest Neighbours classication. These are used as a non parametric likelihood in a Bayesian formulation with a prior that assumes connectivity of neighbouring voxels. The formulation is solved using the method of Iterated Conditional Modes (ICM).
The parameters of the method are found through leave-one-out cross validation on training data after which it is evaluated on previously unseen test data. The multi modal features investigated are 3 structural MRI modalities, the diusion MRI measures of Fractional Anisotropy (FA), Mean Diusivity (MD) and several spatial features.
Results show a benet from the inclusion of diusion primarily to the most dicult cases. Results shows that combining probabilistic K-Nearest Neighbour with a Markov Random Field formulation leads to a slight improvement of segmentations.
Language: | English |
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Publisher: | Springer |
Year: | 2012 |
Pages: | 156-163 |
Proceedings: | International Conference on Image Analysis and Recognition, ICIAR 2012 |
Journal subtitle: | Springer Lecture Notes |
ISBN: | 3642312977 , 3642312985 , 9783642312977 and 9783642312984 |
Types: | Conference paper |
DOI: | 10.1007/978-3-642-31298-4_19 |
ORCIDs: | Larsen, Rasmus |