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10 items by relevance
1 Book chapter

Controlling the outcome: how extremely short laser pulses can help us in the future

Bache, Morten

Beyond Optical Horizons — 2009, pp. 91-108

Year: 2009

Language: English

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2 Journal article

Hyaluronic Acid versus Platelet-Rich Plasma: Double-blind Randomized Controlled Trial Comparing Clinical Outcomes and Intra-Articular Biology for Treatment of Knee Arthritis : Double-blind Randomized Controlled Trial Comparing Clinical Outcomes and Intra-Articular Biology for Treatment of Knee Arthritis

Cole, Brian J.; Fortier, Lisa A.; Karas, Vasili; Hussey, Kristen Elizabeth; Tilton, Annemarie K.; Merkow, David B.; et al. (3 more)

Orthopaedic Journal of Sports Medicine — 2015, Volume 3, Issue 7 suppl2, pp. 2325967115S0012

Osteoarthritis (OA) is a debilitating disease that, in some form, affects up to 47 million Americans each year and is estimated to affect 67 million by 2030. Hyaluronic acid (HA) is currently utilized as an intra-articular injection for treatment of patients with knee OA. A movement in biochemical research has emerged that focuses on analysis of catabolic and anabolic growth factors of the joint. It is proposed that platelet-rich plasma (PRP) is a biologic alternative to HA that may alter the intra-articular biologic milieu to mitigate the symptoms of OA. The purpose of this double-blind pr...

Year: 2015

Language: Undetermined

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3 Journal article

How the rate of change and control of a modular product architecture impact firm‐level outcomes

Galvin, Peter; Burton, Nicholas; Bach, Norbert; Rice, John

Strategic Change — 2020, Volume 29, Issue 1, pp. 67-76

Who controls a product architecture and the rate at which this architecture changes, impacts the type of outcomes a firm can expect to derive from utilizing a modular product architecture? Advantages such as increased levels of innovation, quick determination of consumer preferences and lower

Year: 2020

Language: Undetermined

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4 Journal article · Conference paper

The NCRI future of surgery initiative: Defining a research agenda for outcomes of surgical randomized controlled trials

McNair, Angus; Brock, Kristian; Jones, Terry; Francis, Adele; Blazeby, Jane; Bach, Simon; et al. (3 more)

Ejso — 2016, Volume 42, Issue 11, pp. S229-S230

Year: 2016

Language: English

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5 Journal article

Pathophysiology and Outcomes of Endothelium Function in Coronary Microvascular Diseases: A Systematic Review of Randomized Controlled Trials and Multicenter Study

Avtaar Singh, Sanjeet Singh; Nappi, Francesco

Biomedicines — 2022, Volume 10, Issue 12

strategy was performed using a dataset that has previously been published. Data of pooled analysis include research articles (human and animal models), CABG, and PCI randomized controlled trials (RCTs). Details of the search strategy and the methods used for data pooling have been published previously

Year: 2022

Language: English

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6 Journal article

Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial

Nass, Ralf; Pezzoli, Suzan S.; Oliveri, Mary Clancy; Patrie, James T.; Harrell, Frank E.; Clasey, Jody L.; et al. (4 more)

Annals of Internal Medicine — 2009, Volume 149, Issue 9, pp. 601-611

Growth hormone (GH) secretion and muscle mass decline from mid-puberty throughout life culminating in sarcopenia, frailty, decreased function and loss of independence. Determine if an oral ghrelin mimetic (MK-677) would enhance GH secretion into the young adult range without serious adverse effects, prevent the decline of fat-free mass (FFM), and decrease abdominal visceral fat (AVF) in healthy older adults. Two-year, double-blind, randomized, placebo-controlled, modified-crossover clinical trial. General Clinical Research Center study performed at a University Hospital. Sixty-five healthy ...

Year: 2009

Language: English

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7 Journal article

Effects of Dimeric PSD-95 Inhibition on Excitotoxic Cell Death and Outcome After Controlled Cortical Impact in Rats

Sommer, Jens Bak; Bach, Anders; Malá, Hana; Gynther, Mikko; Bjerre, Ann-Sofie; Gram, Marie Gajhede; et al. (4 more)

Neurochemical Research — 2017, Volume 42, Issue 12, pp. 3401-3413

be an effective therapeutic strategy in TBI. The objectives of the present study were to assess the effects of a dimeric inhibitor of PSD-95, UCCB01-144, on excitotoxic cell death in vitro and outcome after experimental TBI in rats in vivo. In addition, the pharmacokinetic parameters of UCCB01-144 were

Year: 2017

Language: English

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8 Journal article

Effect of Micronutrients and L-Carnitine as Antioxidant on Sperm Parameters, Genome Integrity, and ICSI Outcomes: Randomized, Double-Blind, and Placebo-Controlled Clinical Trial

Lahimer, Marwa; Gherissi, Oumaima; Ben Salem, Nesrine; Ben Mustapha, Henda; Bach, Véronique; Khorsi-Cauet, Hafida; et al. (4 more)

Antioxidants — 2023, Volume 12, Issue 11

The evaluation of sperm DNA integrity is recommended in the sixth edition of the 2021 World Health Organization guidelines. Oxidative stress has been identified as a crucial factor leading to genome decay, lipid peroxidation, and nucleoprotein oxidation. This double-blind, placebo-controlled

Year: 2023

Language: English

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9 Journal article

Clinical and functional outcomes after anterior cruciate ligament reconstruction using cortical button fixation versus transfemoral suspensory fixation: a systematic review of randomized controlled trials

Saccomanno, Maristella F; Shin, Jason J; Mascarenhas, Randy; Haro, Marc; Verma, Nikhil N; Cole, Brian J; et al. (1 more)

Arthroscopy — 2014, Volume 30, Issue 11, pp. 1491-1498

To compare clinical and functional outcomes after anterior cruciate ligament (ACL) reconstruction using cortical button versus transfemoral suspensory fixation. This systematic review was conducted following the Cochrane handbook guidelines and PROSPERO registration. Only Level I and II randomized

Year: 2014

Language: English

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10 Journal article

Elbasvir plus grazoprevir in patients with hepatitis C virus infection and stage 4-5 chronic kidney disease: clinical, virological, and health-related quality-of-life outcomes from a phase 3, multicentre, randomised, double-blind, placebo-controlled trial

Bruchfeld, Annette; Roth, David; Martin, Paul; Nelson, David R; Pol, Stanislas; Londoño, Maria-Carlota; et al. (9 more)

Lancet. Gastroenterology and Hepatology — 2017, Volume 2, Issue 8, pp. 585-594

response (SVR), safety data, health-related quality-of-life (HRQOL), and virological resistance analyses in patients in C-SURFER who received immediate antiviral therapy or who received placebo before therapy. In this phase 3, multicentre, randomised, placebo-controlled study, we randomly assigned adults

Year: 2017

Language: English

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