Book chapter
A Methodology for Development of a Pedagogical Simulation Tool used in Fermentation Applications
Department of Chemical and Biochemical Engineering, Technical University of Denmark1
KT Consortium, Department of Chemical and Biochemical Engineering, Technical University of Denmark2
PROSYS - Process and Systems Engineering Centre, Department of Chemical and Biochemical Engineering, Technical University of Denmark3
Aalborg University4
Department of Applied Mathematics and Computer Science, Technical University of Denmark5
Statistics and Data Analysis, Department of Applied Mathematics and Computer Science, Technical University of Denmark6
In this work, a holistic methodology was developed and implemented in a computeraided framework with the purpose of establishing a pedagogical simulation tool for bioprocess applications. The methodology integrates the development of a process simulator with the use of gamification elements to improve the pedagogical experience.
Moreover, model development and reuse was incorporated into the framework through creating a generic model template. The application of the methodology was demonstrated by the simulation of a batch fermentation process of Saccharomyces cerevisiae cultivated under aerobic conditions with glucose as substrate, thereby, demonstrating mixed metabolism dynamics and considering the inhibition of ethanol consumption due to the presence of glucose with an integrated learning design and gamification elements.
The learning experience, done with beta users with different previous levels of knowledge about fermentation processes, confirmed an interest for using gamification for training chemical engineering, biochemical engineering, and biotechnology students.
Language: | English |
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Publisher: | Elsevier |
Year: | 2018 |
Pages: | 1621-1626 |
Proceedings: | 13th International Symposium on Process Systems Engineering (PSE 2018) |
Series: | Computer Aided Chemical Engineering |
ISBN: | 0444642412 , 0444642420 , 9780444642417 and 9780444642424 |
ISSN: | 15707946 |
Types: | Book chapter |
DOI: | 10.1016/B978-0-444-64241-7.50265-2 |
ORCIDs: | de las Heras, Simoneta Caño , Mansouri, Seyed Soheil , Weitze, Charlotte Lærke , Gernaey, Krist V. , Rootzén, Helle and Krühne, Ulrich |