Conference paper
Biochips: The Integrated Circuit of Biology
Department of Informatics and Mathematical Modeling, Technical University of Denmark1
Computer Science and Engineering, Department of Informatics and Mathematical Modeling, Technical University of Denmark2
Embedded Systems Engineering, Department of Informatics and Mathematical Modeling, Technical University of Denmark3
Microfluidic biochips integrate different biochemical analysis functionalities (e.g., dispensers, filters, mixers, separators, detectors) on-chip, miniaturizing the macroscopic chemical and biological processes often processed by lab-robots, to a sub-millimeter scale. These microsystems offer several advantages over the conventional biochemical analyzers, e.g., reduced sample and reagent volumes, speeded up biochemical reactions, ultra-sensitive detection and higher system throughput, with several assays being integrated on the same chip.
Hence, microfluidic biochips are replacing the conventional biochemical analyzers, and areable to integrate on-chip all the necessary functions for biochemical analysis. Microfluidic biochips have an immense potential in multiple application areas, such as clinical diagnostics, advanced sequencing, drug discovery, and environmental monitoring, to name a few.
Consequently, over the last decade, biochips have received significant attention both in academia and industry. The International Technology Roadmap for Semiconductors 2011 has listed “Medical” as a “Market Driver” for the future, and many companies related to biochips have already emerged in recent years and have reported significant profits.
Language: | English |
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Publisher: | IEEE |
Year: | 2012 |
Pages: | 1-1 |
Proceedings: | 2012 IEEE 30th NORCHIP ConferenceNORCHIP |
ISBN: | 1467322210 , 1467322229 , 1467322237 , 9781467322218 , 9781467322225 and 9781467322232 |
Types: | Conference paper |
DOI: | 10.1109/NORCHP.2012.6403135 |
ORCIDs: | Madsen, Jan |
Biology CAD CAD tools Computer Aided Design Robots advanced sequencing bioMEMS biochemical analysis biochemical analyzer biochemical reaction biochemistry chip integrated microvalve clinical diagnostics device level physical modeling droplet based biochip drug discovery drugs electrode array environmental monitoringintegrated circuit lab robots lab-on-a-chip microfluidic biochips microfluidics micropumps microsystems mixers multicore microelectronic platform multiplexers ultrasensitive detection