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Conference paper

Identifying modular relations in complex brain networks

From

Department of Informatics and Mathematical Modeling, Technical University of Denmark1

Cognitive Systems, Department of Informatics and Mathematical Modeling, Technical University of Denmark2

Copenhagen University Hospital Herlev and Gentofte3

We evaluate the infinite relational model (IRM) against two simpler alternative nonparametric Bayesian models for identifying structures in multi subject brain networks. The models are evaluated for their ability to predict new data and infer reproducible structures. Prediction and reproducibility are measured within the data driven NPAIRS split-half framework.

Using synthetic data drawn from each of the generative models we show that the IRM model outperforms the two competing models when data contain relational structure. For data drawn from the other two simpler models the IRM does not overfit and obtains comparable reproducibility and predictability. For resting state functional magnetic resonance imaging data from 30 healthy controls the IRM model is also superior to the two simpler alternatives, suggesting that brain networks indeed exhibit universal complex relational structure in the population.

Language: English
Publisher: IEEE
Year: 2012
Pages: 1-6
Proceedings: 2012 IEEE International Workshop on Machine Learning for Signal Processing
Series: Machine Learning for Signal Processing
ISBN: 1467310247 , 1467310255 , 1467310263 , 9781467310246 , 9781467310253 and 9781467310260
ISSN: 21610363 and 15512541
Types: Conference paper
DOI: 10.1109/MLSP.2012.6349739
ORCIDs: Mørup, Morten and Hansen, Lars Kai

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