Conference paper
Simplified Monolithic Flow Cytometer Chip With Three-Dimensional Hydrodyanmic Focusing And Integrated Fiber-Free Optics
In
Proceedings of 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences
—
2011, pp. 1888-1890
Abstract
A miniaturized flow cytometry incorporating both fluidic and optical systems has a great possibility for portable biochemical sensing or point-of-care diagnostics. This paper presents a simple microfluidic flow cytometer combining reliable 3D hydrodynamic focusing and optical detection without optical fibers in a monolithic architecture fabricated by a single photolithographic process.
The vertical flow focusing is achieved by the optimized inlet geometry in a PDMS lid onto the substrate with detection channel and integrated optics. The simplified approach indicates the possibility to be applied as a portable platform of cytometer chip.
| Language: | English |
|---|---|
| Year: | 2011 |
| Pages: | 1888-1890 |
| Proceedings: | 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Types: | Conference paper |
