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10 items by relevance
1 Book chapter

Causal mapping

Hansen, Mette Sanne; Rasmussen, Lauge Baungaard

Facilitating Change — 2011, pp. 257-284

Year: 2011

Language: English

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2 Journal article

Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

Gaulton, Kyle J; Ferreira, Teresa; Lee, Yeji; Raimondo, Anne; Mägi, Reedik; Reschen, Michael E; et al. (212 more)

Nature Genetics — 2016, Volume 47, Issue 12, pp. 1415-1425

We performed fine-mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in/near KCNQ1. “Credible sets” of variants most likely to drive each distinct signal

Year: 2016

Language: Undetermined

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3 Conference paper

Potential Regulator and Causal Genes for Boar Taint in Pigs from genome-transcriptome (eQTL) mapping analyses

Drag, Markus Hodal; Hansen, Mathias Brygger; Kadarmideen, Haja N

Year: 2017

Language: English

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4 Journal article

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Vigorito, Elena; Kuchenbaecker, Karoline B.; Beesley, Jonathan; Adlard, Julian; Agnarsson, Bjarni A.; Andrulis, Irene L.; et al. (139 more)

Plos One — 2019, Volume 11, Issue 7, pp. e0158801

Population-based genome wide association studies have identified a locus at 9p22.2 associated with ovarian cancer risk, which also modifies ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. We conducted fine-scale mapping at 9p22.2 to identify potential causal variants in BRCA1 and BRCA2

Year: 2019

Language: Undetermined

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5 Dataset

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Vigorito, Elena; B. Kuchenbaecker, Karoline; Beesley, Jonathan; Adlard, Julian; A. Agnarsson, Bjarni; L. Andrulis, Irene; et al. (140 more)

Population-based genome wide association studies have identified a locus at 9p22.2 associated with ovarian cancer risk, which also modifies ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. We conducted fine-scale mapping at 9p22.2 to identify potential causal variants in BRCA1 and BRCA2

Year: 2016

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