Conference paper
3D Printed Flow Phantoms With Fiducial Markers for Super-Resolution Ultrasound Imaging
Department of Micro- and Nanotechnology, Technical University of Denmark1
MEMS-AppliedSensors, Department of Micro- and Nanotechnology, Technical University of Denmark2
Biomedical Engineering, Department of Electrical Engineering, Technical University of Denmark3
Department of Electrical Engineering, Technical University of Denmark4
Polymer Microsystems for Cell Processing, Department of Micro- and Nanotechnology, Technical University of Denmark5
The improved resolution provided by ultrasound super-resolution imaging (SRI) sets new demands on the fabrication of phantoms for the validation and verification of the technique. Phantoms should resemble tissue and replicate the 3D nature of tissue vasculature at the microvascular scale. This paper presents a potential method for creating complex 3D phantoms, via 3D printing of water-filled polymer networks.
By using a custom-built stereolithographic printer, projected light of the desired patterns converts an aqueous poly(ethylene glycol) diacrylate (PEGDA) solution into a hydrogel, a material capable of containing 75 wt% of water. Due to the hydrogel mainly consisting of water, it will, from an acoustical point of view, respond very similar to tissue.
A method for printing cavities as small as (100 μm)3 is demonstrated, and a 3D printed flow phantom containing channels with cross sections of (200 μm)2 is presented. The designed structures are geometrically manufactured with a 2% increase in dimensions. The potential for further reduction of the flow phantom channels size, makes 3D printing a promising method for obtaining microvascular-like structures.
Language: | English |
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Publisher: | IEEE |
Year: | 2018 |
Pages: | 1-9 |
Proceedings: | 2018 IEEE International Ultrasonics Symposium |
ISBN: | 1538634252 , 1538634260 , 9781538634257 and 9781538634264 |
ISSN: | 19485727 |
Types: | Conference paper |
DOI: | 10.1109/ULTSYM.2018.8580217 |
ORCIDs: | Ommen, Martin Lind , Villagómez Hoyos, Carlos Armando , Jensen, Jørgen Arendt , Larsen, Niels Bent and Thomsen, Erik Vilain |
3D printed flow phantom 3D printing Attenuation Phantoms Polymers Resins Solids Three-dimensional displays Ultrasonic imaging biomedical ultrasonics blood vessels custom-built stereolithographic printer flow phantom channel flow phantoms hydrogel hydrogels materials preparation microvascular scale microvasculature phantom phantoms poly(ethylene glycol)diacrylate resolution stereolithography super-resolution ultrasound imaging three-dimensional printing tissue vasculature ultrasound water-filled polymer networks