Conference paper
Carbon nanopillars for enhanced stem cell differentiation and dopamine detection
Department of Photonics Engineering, Technical University of Denmark1
Programmable Phase Optics, Department of Photonics Engineering, Technical University of Denmark2
Department of Micro- and Nanotechnology, Technical University of Denmark3
European Commission Joint Research Centre Institute4
Nanoprobes, Department of Micro- and Nanotechnology, Technical University of Denmark5
Center for Intelligent Drug Delivery and Sensing Using Microcontainers and Nanomechanics, Department of Health Technology, Technical University of Denmark6
Biomaterial Microsystems, Department of Micro- and Nanotechnology, Technical University of Denmark7
Polymer Microsystems for Cell Processing, Department of Micro- and Nanotechnology, Technical University of Denmark8
Bioanalytics, Department of Micro- and Nanotechnology, Technical University of Denmark9
Parkinson’s disease is characterized by a deficit of dopamine in the brain, a neurotransmitter involved in the motor function. One of the future ideas for treatment is cell replacement therapy. Our group has previously shown that pyrolysed 3D carbon micropillars induce spontaneous differentiation of human neural stem cells (hNSCs) into dopaminergic neurons and that they can also be employed for detecting dopamine release from mature neurons attached to them [1].
Here, we report 3D carbon nanopillars, fabricated through colloidal lithography, with even more pronounced effect on the electrochemical detection of dopamine
| Language: | English |
|---|---|
| Year: | 2016 |
| Proceedings: | Biosensors 2016 |
| Types: | Conference paper |
| ORCIDs: | Bunea, Ada-Ioana , Keller, Stephan Sylvest , Larsen, Niels Bent , Heiskanen, Arto and Emnéus, Jenny |
