Conference paper
Validation of a Simulation Model Describing the Glucose-Insulin-Glucagon Pharmacodynamics in Patients with Type 1 Diabetes
Department of Applied Mathematics and Computer Science, Technical University of Denmark1
Scientific Computing, Department of Applied Mathematics and Computer Science, Technical University of Denmark2
Copenhagen University Hospital Herlev and Gentofte3
Dynamical Systems, Department of Applied Mathematics and Computer Science, Technical University of Denmark4
Zealand Pharma A/S5
University of Copenhagen6
Copenhagen Center for Health Technology, Centers, Technical University of Denmark7
Center for Energy Resources Engineering, Centers, Technical University of Denmark8
Currently, no consensus exists on a model describing endogenous glucose production (EGP) as a function of glucagon concentrations. Reliable simulations to determine the glucagon dose preventing or treating hypoglycemia or to tune a dual-hormone artificial pancreas control algorithm need a validated glucoregulatory model including the effect of glucagon.
Language: | English |
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Year: | 2017 |
Proceedings: | Advanced Technology and Treatments for Diabetes 2017 |
Types: | Conference paper |
ORCIDs: | Wendt, Sabrina Lyngbye , Møller, Jan Kloppenborg , Madsen, Henrik and Jørgensen, John Bagterp |